EMIDONE (Domperidone) 10mg Tablets

DRUG CATEGORY: Antidopaminergic / Gastroprokinetic

MECHANISM OF ACTION: The gastroprokinetic properties are related to its peripheral dopamine receptor blocking properties. Domperidone facilitates gastric emptying and decreases small bowel transit time by increasing esophageal and gastric peristalsis and by lowering esophageal sphincter pressure. Antiemetic: The antiemetic properties are related to its dopamine receptor blocking activity at both the chemoreceptor trigger zone and at the gastric level. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone.

INDICATIONS: Acute nausea and vomiting, Dyspepsia, Functional dyspepsia, Gastric distension pain due to pressure on the stomach, Gastro-oesophageal reflux disease, Nausea and vomiting, Non-ulcer dyspepsia, Reflux oesophagitis.

DOSAGE AND ADMINISTRATION: One tablet 3-4 times daily 15-30 minutes before meals and if necessary, before retiring to

PRESENTATION: EMIDONE Tablets are available in blister pack of 3×10’s Tablets.