Antifen (Ketotifen) 60ml Syrup (0.2mg/ml)

DRUG CATEGORY: Antiasthmatic / Antiallergic

MECHANISM OF ACTION: Ketotifen is a relatively selective, non-competitive histamine antagonist (H1-receptor) and mast cell stabilizer. Ketotifen inhibits the release of mediators from mast cells involved in hypersensitivity reactions. Decreased chemotaxis and activation of eosinophils has also been demonstrated.

INDICATIONS: Asthma, atopic (prophylaxis), chronic treatment of mild atopic asthmatic children. Ketotifen is a prophylactic agent to be used on a continuous basis. Prevention and treatment of allergic rhinitis and allergic skin reactions.

DOSAGE AND ADMINISTRATION: Usual adult and adolescent dose Asthma, atopic (prophylaxis) Oral, 5 mL (1 mg) twice daily, in the morning and evening. Usual pediatric dose Asthma, atopic (prophylaxis) Infants and children 6 months to 3 years of age: Oral, 0.25 mL (50 mcg or 0.05 mg) per kg of body weight twice daily, in the morning and evening. Children older than 3 years of age: See Usual adult and adolescent dose.

PRESENTATION: Antifen syrup is available in bottle of 60ml.